ICSI (Micro Manipulation) Intracytoplasmic sperm injection (ICSI) is an in vitro fertilization (IVF) procedure in which a single sperm cell is injected directly into the cytoplasm of an egg. This technique is used in order to prepare the gametes for the obtention of embryos that may be transferred to a maternal uterus. In this case each egg is fertilized with the help of a very advanced machine called micro-manipulator. The machine allows a sperm to be injected into the egg. This is specially done in cases where there is a problem with the male and especially in cases where sperm is taken out from male with the help of a needle. Decreased sperm count or motility (IVF can usually be done above 5 million per ml; less than 5 million per ml, ICSI is best). Patients with unexplained infertility who have not yet become pregnant with conventional treatment, although all marital tests are normal. Patients who have failed to conceive despite all routine infertility treatments. Patients who wish to become pregnant through the process of donating embryos and eggs Our department's in vitro fertilization success rate is more than 50%, which is comparable to that of leading departments in the world.